All posts by Kharah Ross

Chemistry Postdoctoral Position at UCLA

A unique opportunity for a postdoctoral scholar is currently available at the Crump Institute for Molecular Imaging at the University of California Los Angeles (UCLA). Our team has joined forces with Fuzionaire Diagnostics, a Caltech spin-out company from the laboratory of Prof Bob Grubbs, founded by Anton Toutov (PhD ’16). The Crump Institute provides a unique environment of translational research that aims to develop new technologies to examine the biology of disease, improve molecular diagnostic tools and advance therapeutic developments. Research focuses around positron emission tomography (PET), a powerful imaging tool that provides non-invasive, quantitative information about specific molecular targets and interactions in living organisms and patients.  Molecular imaging is emerging as an essential part of cancer research and clinical care particularly by providing tools for better understanding the biology of disease and its therapeutic modulation.

We are currently seeking a motivated synthetic chemist ready to function in a fast-paced and collaborative environment. The synthetic chemistry candidate for this opportunity will work on novel methods for the synthesis of PET tracers to be evaluated for clinical translation at the Crump Institute for Molecular Imaging.  This candidate will be part of the Murphy group in the Crump Institute and work closely with the Fuzionaire Diagnostics team as well. The goals will be to develop and optimize synthetic routes for the synthesis of [18F]-labeled small-molecules as well as biologics like peptides, proteins and antibodies for pre-clinical imaging studies. Experience in radiochemistry is not required; training will be provided for radiosynthesis with 18F using automated commercial radiosynthesizers.  Applicants should have exceptional communication skills coupled with a strong publication record.

 

Qualifications:

  • D. in Organic Chemistry required with a strong publication record in peer reviewed journals
  • Sound knowledge of organic chemistry reactions, mechanisms, multistep synthesis, and purification techniques
  • Must be able to prioritize work, multi-task and be very well organized
  • Effective problem solving skills
  • Must have demonstrated awareness of safety practices required for working with hazardous chemicals
  • Excellent communication skills (oral and written) with strong work ethic
  • Highly motivated and demonstrates the ability to work efficiently and productively in a dynamic team environment with other scientific disciplines
  • Experience in fluorine and organometallic chemistry is highly desirable

Interested applicants please send a cover letter and curriculum vitae (CV) to Jennifer Murphy at JMMurphy@mednet.ucla.edu.

The UCLA Department of Psychology, Center for Anxiety and Depression Research postdoc

Candidate must have a PhD in clinical psychology. Job responsibilities include helping support the PI in the design and execution of extramurally funded projects examining extinction learning and exposure therapy. The candidate should have a strong background in translational research. In addition, the fellow will supervise graduate students conducting cognitive-behavioral therapy in several randomized clinical trials, as well as clinical assessment of participants in the UCLA Depression Grand Challenge. Responsibilities include assisting the PI in study design, regulatory aspects of research, day-to-day tasks related to project management, data analysis, manuscript preparation, and clinical supervision.

To submit for the position, or to request more information, please contact Kelly Chen at: kellychen@psych.ucla.edu

Postdoctoral position in Cornea Dept

Name of Position: Postdoctoral Fellow

  • Department: Cornea
  • Description: A postdoctoral position is available at the University of California, Los Angeles to study the molecular regulation of human corneal stem cells with an emphasis on translational application. Experimental approaches employed in our laboratory include molecular biology and cell engineering.The successful applicant will investigate the role of Wnt signaling in the regulation of the human limbal stem cells.The applicant will also work in a multidisciplinary setting with basic scientists and clinicians to investigate the optimal conditions to regenerate corneal stem cells. Qualified candidate should have a PhD and/or MD with a strong background in cell biology and molecular biology. We are seeking an independent and motivated individual with excellent organizational, interpersonal, and communication skills (both verbal and written). Please send CV and names of three references to Dr. Sophie Deng.
  • Contact Person: Dr. Sophie Deng email: deng@jsei.ucla.edu

Postdoctoral Fellowship Opportunity Division of Pulmonary and Critical Care Medicine at UCLA

We are seeking applications from qualified candidates for a postdoctoral fellowship performing translation cancer research studying mitochondria biology and metabolism in lung cancer in the laboratory of Dr. David Shackelford in the Division of Pulmonary and Critical Care Medicine at UCLA’s David Geffen School of Medicine. Candidates will need to have expertise in molecular and cellular biology and basic biochemistry. Prior experience working with animal models such as genetically engineered mouse models (GEMMs) and/or patient derived xenografts (PDXs) is encouraged but not required. The job will require performing both in vitro cell line work and in vivo work in GEMMs and PDXs. This includes performing lung tumor induction in GEMMs, lung tumor implantation in PDXs, dosing of mice in therapeutic studies, performing micro PET-CT imaging on mice, microscopy, biochemical analysis of tumor tissue, metabolic analysis of experiments such as isotopomeric tracing and respirometry as well as executing the analysis of all studies. Lastly, the candidate will be expected to analyze and prepare data for publication in peer-reviewed journals as well as present at scientific meetings. This study will require outstanding verbal and written communication skills. The work is highly translational and requires comfort working in a multi-discipline team environment with experts in cancer metabolism, mitochondrial biology, PET imaging, radiochemistry, thoracic surgery, oncology and pathology.

Qualifications: This is an NIH Training Postdoctoral Training Fellowship and candidates must have a Ph.D., M.D. or equivalent and US citizenship or permanent residency.

To apply, please email CV, cover letter, and 3 references to David Shackelford, Ph.D.: dshackelford@mednet.ucla.edu

UCLA Post-doc in Psychoneuroimmunology & Depression Research

The UCLA Laboratory for Stress Assessment and Research (PI: George Slavich) seeks to hire a full-time post-doctoral fellow as soon as possible. This is an NIMH-funded position, with full salary and benefits. Applicants should be fMRI trained and interested in studying neural, immunologic, and genomic mechanisms underlying risk for depression and related health problems in adolescence. Responsibilities will include helping lead and manage an existing multi-level fMRI study protocol, with an outstanding team of RAs; scanning participants; processing and analyzing fMRI data; examining associations between neural, immunologic, genomic, and/or behavioral data; presenting at conferences; and preparing manuscripts for publication. Necessary qualifications: Ph.D. or expected Ph.D. in neuroscience, psychology, or related field; strong prior training in social, affective, and/or cognitive neuroscience, with the ability to independently scan participants; strong fMRI task development and programming skills; evidence of past scientific productivity and future promise; and an interest in immunology and/or social genomics. The lab is based at the Cousins Center for Psychoneuroimmunology in the Semel Institute for Neuroscience and Human Behavior at UCLA (http://www.uclastresslab.org). Self-motivated, highly reliable, scientifically creative individuals from all backgrounds, who are looking to work in an exciting, multi-disciplinary environment, are encouraged to apply. To apply, email a single PDF to George Slavich, Ph.D. (gslavich@mednet.ucla.edu) that includes: (a) one-page (max) cover letter describing past training, current work, future goals, and the contact information for two professional references; (b) updated CV; and (c) 1-2 recent publications. Application reviews will begin immediately and will be considered in the order received (posted: April 18, 2017).

UCLA is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected veteran status.

 

Postdoctoral Scholar – Employee (Radiology)

The Department of Radiological Sciences at the David Geffen School of Medicine at UCLA has an immediate opening for a Postdoctoral Scholar with expertise in multi-dimensional Magnetic Resonance Spectroscopic Imaging and knowledge of MATLAB, C/C++ and MRS/MRI pulse programming skills.

The applicant must have a Ph.D. or equivalent degree relating to MR Physics or biomedical Physics or Biomedical Engineering, and must have hands-on experience in developing novel MR pulse sequence and post-processing algorithms. Previous experience in Data Acquisition and Post-processing in Vivo Magnetic Resonance Spectroscopy and MRI, accelerated MR spectral acquisition (echo-planar /radial/concentric circular/spiral encoding) and post-processing using non-linear reconstruction/compressed sensing is desired. Pulse sequence programming experience on Siemens IDEA platforms is desired. Please contact and send curriculum vitae to the following address:

M. Albert Thomas Ph.D., Professor

Department of Radiological Sciences

David Geffen School of Medicine at UCLA

10833 Le Conte Avenue, CHS#BL428

Los Angeles, CA 90095-1721

The University of California is an Equal Opportunity/Affirmative Action Employer: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Additional contact information:

Erik Aguirre, 310-481-7541, eaguirre@mednet.ucla.edu

https://recruit.apo.ucla.edu/apply/JPF02848

Postdoctoral fellowship in Neuropsychiatric Genomics: Biomarkers of Depression Treatment Response

Our interdisciplinary research group is looking for a self-motivated postdoctoral fellow with a strong computational background to join an initiative aimed at identifying neurobiological changes associated with response to fast-acting treatment interventions for depression. Our current projects incorporate genomic, clinical, neurocognitive, and neuroimaging measures in longitudinal studies, including total sleep deprivation, serial ketamine infusion, and electroconvulsive therapy for the treatment of severe, treatment-resistant depression. The applicant would be primarily responsible for the management and analysis of microarray gene expression data, but would also conduct integrative analyses in collaboration with other team members. The fellow will be expected to conduct several different kinds of analyses of the data (e.g., differential expression, WGCNA, predictive modeling), which will require staying up to date on developments in the field and analysis packages. The fellow will have opportunities to perform innovative studies, and will be expected to present/publish the results in scientific conferences/journals and participate in grant writing. The fellow will also have access to existing datasets that provide additional opportunities to explore relationships between neurocognitive function and genomic activity.

The postdoc should have completed a PhD at a major university in bioinformatics,  computational biology, neuroscience, biostatistics, computer science or related disciplines, with a strong research background, ability to work both independently as well as part of a team, and interest in applying these skills to the topic of depression. This position is collaborative and requires working with individuals from a range of backgrounds. A computational background and ability to handle large data sets is required, with experience in analysis and interpretation of omics data.

Additional qualifications:

 Experience in Unix/Linux shell

 Excellent skills in programming, and proficiency using R for statistical analysis

 Familiarity or experience with array-based genomic data

 Excellent oral and written communication skills

 Experience in psychiatry or neuroscience preferred

 Two-year commitment minimum

The position is based in the UCLA Department of Psychiatry and Biobehavioral Sciences. The fellow will be primarily supervised by Dr. Eliza Congdon; given the interdisciplinary nature of the position, opportunities for supervision are also available through collaborating PIs based on the applicants background and career plans. This position is supported by the UCLA Depression Grand Challenge – a campus-wide initiative aimed at cutting the burden of depression in half by 2050 primarily through the collection of a 100,000-person cohort.

Interested candidates should e-mail their CV, a brief statement of research interest, and the names and e-mails for three references to Eliza Congdon at econgdon@mednet.ucla.edu.

Postdoctoral Research Fellow Position – Semel Institute for Neuroscience and Human Behavior

We are seeking a full-time postdoctoral trainee interested in working on clinical neuroscience and neuroimaging studies of geriatric depression and mind-body interventions.  Experience and interest in neuroimaging and in working with clinical populations and/or older adults are preferred. If you are interested in this opportunity, please contact Helen Lavretsky, MD at hlavretsky@mednet.ucla.edu.

Postdoctoral Research Position in Immunology

The UCLA Immunogenetics Center, Department of Pathology, University of California, Los Angeles (www.hla.ucla.edu) is seeking a highly motivated postdoctoral candidate to join a multidisciplinary team of investigators from UCLA, UCLA-Harbor and Duke University in a translational research project focused on characterizing immunity to methicillin-resistant staphylococcus aureus (MRSA). The project involves profiling innate and adaptive immune responses to understand the mechanisms underlying persistent bacteremia and to identify and validate a signature of persistence or resolution of infection. The postdoctoral fellow will generate high throughput immunophenoptyping, genomic and transcriptomic data and use systems-based statistical and computational immunology to define altered host:pathogen interactions and the role of antibiotics in MRSA persistence. The technologies to be used in this project include multiplex cytokine/chemokines, multiparameter flow cytometry, genomic and transcriptomic platforms, and in vitro manipulation of peripheral blood mononuclear cells.

The candidate will benefit from a highly collaborative and diverse team of investigators including experts in MRSA, immune profiling, statistics, computational immunology at the University of California Los Angeles. Applicant must be an immunology, cell, and/or molecular biology Ph.D. candidate or recent Ph.D. graduate (within the past 2 years).

Experience with tissue culture, immunological assays, and flow cytometry is expected; whereas experience in multidimensional data set analysis is a plus. Good command of the English language (both speaking and writing) is a must. The applicant will be expected to prepare/publish manuscripts, present data at local and international meetings, and participate in seminars/meetings of the Department of Pathology & Laboratory Medicine, and the Immunity, Inflammation, Infection and Transplantation Theme.

The successful candidate must have outstanding achievement in his/her doctoral research and possess independent research abilities and ambitious scientific goals. Please submit your cover letter, CV, and names and contact information for at least 3 references to: https://recruit.apo.ucla.edu/apply/JPF02695

UCLA is an affirmative action/equal opportunity employer with a strong institutional commitment to the achievement of faculty and staff diversity. As a campus with a diverse student body, we encourage applications from women, minorities, and individuals with a history of mentoring under-represented minorities in the sciences.

Deadline for applications: December 30, 2016