Postdoctoral Research position in Drug Discovery

We are seeking an exceptional scientist to join the Drug Discovery Laboratory in the Department of Neurology at UCLA. The researcher will have a strong chemistry background and will be involved in exploratory medicinal chemistry efforts on hits and hit-to-lead optimization.

The researcher would apply flow-chemistry techniques using the Syrris Asia system for analog preparation. The laboratory is well equipped and includes a benchtop mass spectrometer and benchtop NMR, for reaction monitoring. The researcher will participate in selection of screening hits, modeling for prediction of new analogs for synthesis, analog preparation, and in vitro ADME/T analysis on leads. The candidate will have the opportunity to present their drug discovery research at collaboration team meetings, and as appropriate at National meetings. The candidate will be encouraged to publish in high-impact journals and given the opportunity to collaborate with renowned international teams.

Required

  • Ph.D. in Chemistry.
  • Familiarity and interest in flow chemistry approaches.
  • Familiarity with structure activity relationship (SAR) and maintenance of chemical databases using Mac, Linux, or Windows systems.
  • Familiarity with modeling and computational analysis.
  • Familiarity with searching programs such as SciFinder and Reaxys

Preference will be given to candidates who have experience in flow chemistry and flow chemistry related techniques.

Starting date is flexible but preference would be given to those who can start as early as January 2015. A commitment of at least one year is required.

Applications (resume and name of 3 references) should be emailed to vjohn@mednet.ucla.edu with subject [drug discover scientist UCLA].